2015

1. Leong, C. R., H. Oshiumi, M. Okamoto, M. Azuma, H Takaki, M. Matsumoto, K.Chayama, and T. Seya. 2015. A MAVS/TICAM-1-Independent Interferon-Inducing Pathway Contributes to Regulation of Hepatitis B Virus Replication in the Mouse Hydrodynamic Injection Model. J. Innate Immun. 7: 47-58.
2. Kasamatsu, J., S. Takahashi, M. Azuma, M. Matsumoto, A. Morii-Sakai, M. Imamura, T. Teshima, A. Takahashi, Y. Hirohashi, T. Torigoe, N. Sato, and T. Seya. 2015. PolyI:C and mouse survivin artificially embedding human 2B peptide induce a CD4+ T cell response to autologous survivin in HLA-A*2402 transgenic mice. Immunobiol. 220: 74-82.
3. Matsumoto, M., M. Tatematsu, F. Nishikawa, M. Azuma, H. Shime, and T. Seya. 2015. Defined TLR3-specific adjuvant that induces NK and cytotoxic T cell activation without significant cytokine production in vivo. Nat Commun. 6:e6280.
4. Maruyama, A., H. Shime, Y. Takeda, M. Azuma, M. Matsumoto, and T. Seya. 2015. Pam2 lipopeptides systemically increase myeloid-derived suppressor cells through TLR2 signaling. Biochem Biophys Res Commun. 457:445-450.
5. Funami, K., M. Matsumoto, N. Ishii, M. Tatematsu, Y. Enokizono, F. Inagaki, H. Oshiumi, and T. Seya. 2015. A determinant for inner membrane localization in the TIR domain of TICAM-2: A regulator for TLR4-mediated TICAM-1 signaling. J. Immunol. 195:4456-4465.
6. Takemura, R., H. Takaki, S. Okada, H. Shime, H. Oshiumi, T. Akazawa, M. Matsumoto, T. Tejima, and T. Seya. 2015. PolyI:C-induced, TLR3/RIP3-dependent necroptosis backs up immune effector-mediated tumor elimination in vivo. Cancer Immunol Res. 3:902-914.
7. Takashima, K., H. Oshiumi, H. Takaki, M. Matsumoto, and T. Seya. 2015. RIOK-mediated phosphorylation of the MDA5 C-terminal region interferes with MDA5 assembly and attenuates MDA5-mediated antiviral innate immune response. Cell Reports. S2211-1247.
8. Oshiumi, H., M. Miyashita, M. Okamoto, Y. Morioka, M. Okabe, M. Matsumoto, and T. Seya. 2015. Dual roles of DDX60 in antiviral innate immunity and regulation of DDX60 functions by epidermal growth factor. Cell Reports. 11:1193-1207.
9. Romanets, O., L. M. Kovalevska, T. Seya, S. P. Sidorenko, and B. Horvat. 2015. Interaction of Measles virus hemagglutinin with CD150-expressing dendritic cells is sufficient to induce immunosuppression. Cell Molec Immunol. 2015 Jun 15.doi:10.1038/cmi.2015.55.
10. Tatematsu, M., K. Funami, N. Ishii, T. Seya, C. Obuse, M. Matsumoto. 2015. LRRC59 is involved in trafficking of nucleic acid-sensing TLRs from the ER. J Immunol. 195:4933-4942.
11. [Errortum] Ebihara, T., T. Seya. 2015. Errortum: Identification of a polyIC-inducible membrane protein that participates in dendritic cell-mediated NK cell activation. J Exp Med. 212:1337.
12. Sato, H., H. Oshiumi, H. Takaki, M. Matsumoto, H. Hikono, and T. Seya. 2015. Evolution of the DEAD box helicase family in the chicken: chicken has no DHX9 orthologue.Microbiol Immunol.59: 633-640.
13. Seya. T., H. Shime, and M. Matsumoto. 2015. Functional alteration of tumor-infiltrating myeloid cells in RNA adjuvant therapy. Anticancer Res.35: 4385-4392.
14. Seya, T., Y. Takeda, and M. Matsumoto. 2015. Tumor vaccines with dsRNA adjuvant ARNAX induces antigen-specific tumor shrinkage without cytokinemia. Oncoimmunol. (in press), 2015.
15. Leong, C. R., M. Matsumoto, T. Suzuki, H. Oshiumi, and T. Seya. 2015. Nucleic acid sensors involved in the recognition of hepatitis B virus (HBV) in the liver-specific in vivo transfection mouse models-Pattern recognition receptors and sensors for HBV. Med Sciences. 3: 16-24.
16. Nakai, M., H. Oshiumi, K. Funami, M. Matsumoto, T. Seya and N. Sakamoto. 2015. Interferon (IFN)- in innate immune response during infection with HCV. Sensors15: 27160-27173.
17. Seya, T., H. Shime, Y. Takeda, M. Tatematsu, K. Takashima, and M. Matsumoto. 2015. Adjuvant for vaccine immunotherapy of cancer - focusing on TLR2 and TLR3 agonists for safe enhancing antitumor immunity. Cancer Sci.Sep 23. doi: 10.1111/cas.12824.
18. Takaki, H., H. Shime, M. Matsumoto, and T. Seya. 2015. Tumor cell death by pattern-sensing of exogenous RNA: tumor cell TLR3 directly induces necroptosis by polyI:C in vivo,independent of immune effector-mediated tumor shrinkage. Oncoimmunol. (in press)
19. Takashima, K., H. Oshiumi, T. Seya. 2015. RIOK3 keeps MDA5 inactive.Oncotarget. 6:30423-30424.